If the GOP nominates Ted Cruz or Rand Paul will it be a Goldwater redux?

In the video above Luke Russert suggested that if the Republicans nominate Ted Cruz or Rand Paul it could be a Goldwater moment.

Rand Paul - Ted Cruz

Barry Goldwater, like Ted Cruz and Rand Paul, was uber conservative. Goldwater justifiably wore the nickname “Mr. Conservative.”

Will an uber conservative ever again be elected President? The last one to occupy the White House was Calvin Coolidge, Warren G. Harding’s Vice President who became President after the death of Harding and was was elected President in his own right in 1924.

I voted for Barry Goldwater in 1964 (yes, I am that old) knowing that he had no chance of being elected because he was too conservative to win a national election just as Ted Cruz and Rand Paul are too conservative to win a national election today.

Link here and here.