A Malaysian Airlines Boeing 777 passenger plane carrying 295 people was shot down with ground-to-air missile at 33,000ft over Ukraine near the Russian border. There were no survivors.
The aircraft was flying from Amsterdam to Kuala Lumpur and came down near the city of Donetsk, a stronghold of pro-Russian rebels, after it was hit by a ground-to-air missile.
A Ukrainian official was quoted as saying the plane disappeared from radar when it was flying at 10,000 meters (33,000 feet), a typical cruising altitude for airliners.
The plane came down at Torez, near Shakhtersk, some 40 km (25 miles) from the Russia border. The area has been the scene of fighting between Ukrainian troops and pro-Russian rebels.
Ukraine has accused Russia of taking an active role in the four-month-old conflict in recent days and accused it earlier on Thursday of shooting down a Ukrainian fighter jet - an accusation that Moscow denied.